Silk (Cindy Moon) in Spider-Man/Deadpool issue #50 pointing at another version of herself from a different issue

Notes:

In the 50th issue of the Spider-Man/Deadpool Marvel comics, Deadpool, along with the help of Gwenpool, jumps to different comics and pulls out heroes from them to bring them back to Hollywood, in order to help defeat The Manipulator. One of the heroes he pulls out is Silk from a past parody comic called "Silk and The Murder Sharks," and as soon as she lands in Hollywood, she finds the future version of herself and the two point at each other in the same manner as the infamous meme. Deadpool then goes so far as to ask the the editors to feature a blank version of the panel for quote "meme purposes."